STEM CELL THERAPY RESEARCH ARTICLES intra-v

Stem cell therapy, a groundbreaking field in medical research, holds immense promise for revolutionizing the treatment of various diseases and injuries. As we stand on the cusp of a new era in healthcare, it's crucial to examine the current state of stem cell therapy research — exploring recent advances, addressing challenges, and envisioning the future of this transformative field.

1. Stromal cells and progenitor cells for osteoarticular regeneration: This research is focused on the use of stromal cells and progenitor cells for the regeneration of osteo-articular tissues.

2. Organoids and Tissue/Organ Chips: This research is exploring the use of organoids and tissue/organ chips in stem cell research.

3. Stem cell therapy of COVID-19 and other respiratory diseases: Scientists are investigating the potential of stem cell therapy in treating COVID-19 and other respiratory diseases.

4. Adult stem cells in retinal diseases: This research is looking into the role of adult stem cells in retinal diseases.

5. Vascular organoids: Researchers are studying the advantages, applications, challenges, and disease modelling strategies of vascular organoids.

6. Stem cells: past, present, and future: This paper reviews the discovery of different stem cells and the potential therapies based on these cells.

7. Disease programs and clinical trials: California’s Stem Cell Agency provides a detailed list of the disease programs and clinical trials currently underway in stem cell research.

8. Adult stem cells in retinal diseases

9. Stem cell therapy of COVID-19 and other respiratory diseases - Guest edited by Hong-Long James Ji (University of Texas Health Science Center at Tyler), Michael A. Matthay (University of California, San Francisco) and Yuanlin Song (Fudan University)

10. CAR T cells in solid tumors: challenges and opportunities - Faroogh Marofi, Roza Motavalli, Vladimir A. Safonov, Lakshmi Thangavelu, Alexei Valerievich Yumashev, Markov Alexander, Navid Shomali, Max Stanley Chartrand, Yashwant Pathak, Mostafa Jarahian, Sepideh Izadi, Ali Hassanzadeh, Naghmeh Shirafkan, Safa Tahmasebi & Farhad Motavalli Khiavi

11. Stem cells: a potential treatment option for kidney diseases - The prevalence of kidney diseases is emerging as a public health problem. Stem cells (SCs), currently considered as a promising tool for therapeutic application, have aroused considerable interest and expectations.

Research on Stem Cell Therapy for Parkinson’s Disease

The promise and potential of stem cells in Parkinson’s disease1: This article discusses the potential of stem cells in treating Parkinson’s disease. It mentions a clinical trial led by Neurosurgeon Viviane Tabar, who is injecting stem cells into the brains of people with Parkinson’s disease to restore dopamine levels1.

1. Radical new therapy for Parkinson’s will use stem cell transplants2: This article talks about a new treatment for Parkinson’s disease involving tissue transplants. The treatment uses lab-grown stem cells transformed into nerve cells to replace those destroyed by the disease2.

2. Revolutionizing the treatment of Parkinson’s patients3: This article highlights a new method that uses genetically engineered stem cells to produce dopaminergic cells, which are crucial for treating Parkinson’s3.

3. Current Status of Stem Cell-Derived Therapies for Parkinson4: This article provides updates on the current progress in stem cell-derived DA neuron transplantation as a therapeutic alternative for Parkinson’s disease4.

4. Stem Cells to the Rescue: A Game Changer for Parkinson’s Patients5: This article showcases a novel method for increasing the purity of dopamine cells derived from genetically engineered stem cells, offering significant potential in treating Parkinson’s disease5.

Research on Stem Cell Therapy for TYPE 2 DIABETES

Towards a stem-cell therapy for diabetes1: This article discusses the potential of stem cells in treating diabetes. It mentions the isolation of the first human embryonic stem cell (hESC) lines in 1998 and how it opened the possibility of stem cell therapies for a variety of conditions, including Type 1 diabetes1.

1. Stem cell-based therapy for type 2 diabetes shows promise2: This article reveals how a combination of stem cell transplantation and antidiabetic medication successfully treated mice with type 2 diabetes2.

2. Treatment of type 2 diabetes mellitus with stem cells and …3: This review details the latest progress and ongoing studies related to the amalgamation of stem cells and antidiabetic drugs3.

3. Stem cell therapy could reverse Type 2 diabetes for some, study finds4: This study suggests that stem cell therapy using cells produced from a patient’s own bone marrow may reduce reliance on insulin or other medications for Type 2 diabetes treatment4.

RESEARCH ON STEM CELL THERAPY FOR HEART CONDITIONS

Here are some of the latest research articles on stem cell therapy for heart conditions:

1. Stem cell–derived heart cells injected into first patient: The Japanese biotech firm Heartseed and Danish pharmaceutical company Novo Nordisk have announced successful dosing of the first patient with their investigational cell therapy for severe heart failure. The first-in-human LAPiS phase 1/2 dose-escalation study uses heart muscle cells differentiated in vitro from induced pluripotent stem cells (iPSCs). The cardiomyocytes are injected directly into the patient’s heart muscle during a coronary bypass operation1.

2. Repairing the heart with stem cells: A new treatment using stem cells—which have the potential to grow into a variety of heart cell types—could potentially repair and regenerate damaged heart tissue. In a study, researchers treated 17 heart attack patients with an infusion of stem cells taken from their own hearts. A year after the procedure, the amount of scar tissue had shrunk by about 50%2.

3. Stem cell therapy may reduce risk of heart attack and stroke: A single administration of adult stem cells directly into an inflamed heart, through a catheter, could result in a long-term 58% reduced risk of heart attack or stroke among heart failure patients with reduced ejection fraction3.

4. Stem Cell Therapy Boosts Quality of Life for People With Advanced Heart: Patients with advanced heart failure can benefit from stem cell therapy, a large, new clinical trial has found. Injections of stem cells programmed to heal damaged heart tissue wound up improving overall quality of life for heart failure patients4.